News

Alpine’s Dual Inhibitor ALPN-101 Reduces Immune Cell Activation in Preclinical Models of Sjögren’s Syndrome

Alpine Immune Sciences‘ ALPN-101, a treatment for inflammatory and autoimmune diseases that works by inhibiting two key pathways — ICOS and CD38 — is better at reducing immune cell activity than a combination of treatments targeting these molecules individually, suggests a study in cells and animal models of Sjögren’s…

HHS Secretary Alex Azar Touts White House Efforts to Cure Rare Diseases

Despite skyrocketing healthcare costs, President Trump is committed to protecting the 30 million or so Americans with rare diseases and ensuring timely, affordable access to lifesaving treatments, the nation’s highest-ranking health official said. “We have to think about how our financing system can protect those with serious and rare illnesses.

Recurrent Aseptic Meningitis Can Be First Symptom of Sjögren’s Syndrome, Case Report Suggests

Doctors should suspect primary Sjögren’s syndrome when examining patients, especially young women, with recurrent aseptic meningitis — a form of inflammation of the meninges, a membrane protecting the brain and spinal cord, that is not caused by bacteria, a case report suggests. The study, “Recurrent aseptic meningitis:…