News

A small RNA molecule may help to drive inflammation in the eyes of people with primary Sjögren’s syndrome (pSS), a new study reports. The findings imply that this molecule, called miR-744-5p, may be a therapeutic target for pSS. The study, “miR-744-5p contributes to ocular inflammation in…

In addition to dry eyes, people with Sjögren syndrome have damage to the surface of their eyes, and those with most extensive damage have high levels of biomarkers linked to inflammation, a study found. People whose syndrome is related to…

While there are few silver linings to the cloud created by COVID-19, the pandemic that has killed tens of thousands, hobbled economies worldwide and drove millions to quarantine in their homes, one may be a new appreciation of telemedicine. “If something good could come out of this crisis, it’s that…

FFF Enterprises and Bionews announced today that both rare and orphan disease advocates are joining forces to provide patients with resources to help them connect as a community and continue to manage their health during this time when many are finding themselves alone. Recognized as the nation’s leading supplier of…

Alterations in salivary glands that cause immune cell infiltration in Sjӧgren’s syndrome patients may be triggered by changes in the mouth’s bacterial composition, findings from a recent study suggest. While many bacterial changes were evident, one particular bacterial species was enough to initiate an inflammatory cascade that contributed in…

Vaginal dryness in women with primary Sjögren’s syndrome may be caused by defective blood vessels and an infiltration of immune cells in their vagina and cervix, a new study suggests. The findings were published in the journal Rheumatology in the study, “Vaginal dryness in primary Sjögren’s…

Seasonal changes do not appear to significantly influence the main symptoms of primary Sjögren’s syndrome — pain, fatigue, and dryness — according to a large study. The study, “Seasonal effect on fatigue, pain and dryness in primary Sjögren’s syndrome,” was published in the journal Arthritis Research…

Poor sleep quality is linked to both fatigue and increased disease activity in primary Sjögren’s syndrome patients, a study reported. Its researchers recommend more study into ways that might help patients with difficulty sleeping, a common problem in this disease. The study, “Correlation of sleep quality with fatigue and disease activity…

People with primary Sjögren’s syndrome who have symptoms outside their glands may carry a higher risk of developing other conditions, such as heart or thyroid disease, and might also be more prone to fractures, according to a study. The findings suggest that making the evaluation of these additional conditions…

The immune cells that produce self-targeting antibodies in cryoglobulinemia vasculitis (CV), a complication of Sjogren’s syndrome, are characterized by mutations that are known to drive lymphomas, a new study suggests. This finding provides clues as to how autoimmune diseases develop, and could open new avenues for diagnosis…