Posts by: Jose Marques Lopes, PhD

News

Having a history of infections, particularly respiratory, skin, and urogenital infections, increases the risk of developing primary Sjögren’s syndrome, according to a population-based study in Sweden. The study, “Infections ... Read more

March 5, 2019

Study Suggests Blocking mTOR Signaling Pathway as Sjogren’s Strategy

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Targeting the mTOR signaling pathway may prevent the increased activation and proliferation of immune cells in the salivary glands of patients with primary Sjögren’s syndrome (pSS), according to new ... Read more

January 15, 2019

Seletalisib Seen to Aid Saliva Production, Lower Inflammation in Mouse Study

News

The PI3K-delta inhibitor known as seletalisib, an investigative treatment for primary Sjögren’s syndrome, improved the production of saliva, lowered the levels of autoantibodies and inflammatory mediators, and decreased immune B- ... Read more

December 13, 2018

Sjogren’s, Lupus Patients Share Gut Microbiota Composition, Study Shows

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Patients with primary Sjogren’s syndrome (pSS) and systemic lupus erythematosus (SLE) share their gut microbial composition, which is different from the general population. Oral microbial composition, however, in different in ... Read more

October 25, 2018

Targeting Specific B-cells May Be Way of Treating Patients’ Chronic Eye Problems, Study Suggests

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Abnormal marginal zone B (MZB)-cells in the lacrimal glands of the eye appear to drive the production of autoantibodies and cause the chronic “dry eye” symptoms patients with Sjogren’s ... Read more

August 14, 2018August 14, 2018

Adiponectin Could Be Salivary Biomarker in Sjogren’s Syndrome, Study Reports

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The hormone adiponectin correlates with disease severity in Sjogren’s syndrome patients, and could be used as a salivary biomarker to diagnose the disease, a Spanish pilot study shows. The research, “Salivary adiponectin, ... Read more

June 19, 2018

Primary Sjogren’s Patients Have Altered Levels, Activity of Immune Cells, Study Finds

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Patients with primary Sjogren’s syndrome (pSS) show altered levels of specific types of immune T-cells and B-cells, which may play an important role in disease activity, new research from ... Read more

May 31, 2018

Big Data Approaches Still Rarely Used to Study Primary Sjogren’s Syndrome, Researchers Find

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Use of big data machine learning to study autoimmune diseases is on the rise, but little focus has been devoted to primary Sjogren’s syndrome (pSS), a French study reports. ... Read more

May 15, 2018

Study Identifies Risk Factors for PAH in Primary Sjogren’s Patients

News

Raynaud’s phenomenon and liver injury are among the risk factors for the development of pulmonary arterial hypertension (PAH) – high blood pressure in the arteries that goes from the heart ... Read more

April 10, 2018April 10, 2018

Dry Mouth Alters Oral Microbiome of Primary Sjögren’s Syndrome Patients, Study Shows

News

Low salivary secretion contributes more to the altered oral microbiome found in people with primary Sjogren’s syndrome (pSS) than does the underlying disease, a Dutch study shows. The research, ... Read more

Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

History of Infections Boosts Risk of Developing Primary Sjögren’s Syndrome, Study Suggests

Study Suggests Blocking mTOR Signaling Pathway as Sjogren’s Strategy

Seletalisib Seen to Aid Saliva Production, Lower Inflammation in Mouse Study

Sjogren’s, Lupus Patients Share Gut Microbiota Composition, Study Shows

Targeting Specific B-cells May Be Way of Treating Patients’ Chronic Eye Problems, Study Suggests

Adiponectin Could Be Salivary Biomarker in Sjogren’s Syndrome, Study Reports

Primary Sjogren’s Patients Have Altered Levels, Activity of Immune Cells, Study Finds

Big Data Approaches Still Rarely Used to Study Primary Sjogren’s Syndrome, Researchers Find

Study Identifies Risk Factors for PAH in Primary Sjogren’s Patients

Dry Mouth Alters Oral Microbiome of Primary Sjögren’s Syndrome Patients, Study Shows

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