News

People with peripheral neuropathy co-occurring with primary Sjögren’s syndrome may see their symptoms ease or even disappear with immunosuppressive therapy, a study found. Researchers observed that Sjögren’s patients who tested positive for certain self-reactive antibodies or had too high levels of proteins called globulins in the blood were at…

Osteoarthritis, rather than inflammatory arthritis, was the more common cause of joint pain among primary Sjögren’s syndrome patients in a small study. While arthritis is associated primarily with inflammation and swelling, osteoarthritis (OA) typically is linked to the mechanical wearing down of joints. Analyses revealed that older age and certain…

Adults with primary Sjögren’s syndrome (pSS) have a higher prevalence of common allergic disorders compared with those with rheumatoid arthritis (RA), another autoimmune condition, a medical records analysis has found. Specifically, food and medicine allergies, nose inflammation known as allergic rhinitis, and eye inflammation called allergic conjunctivitis were found…

Dry eye disease (DED) was found to significantly affect health- and vision-related quality of life in people with Sjögren’s syndrome in a new study. Patients with Sjögren’s “have a lower perceived [life quality] especially in relation to physical and mental wellbeing, correlating to severity of DED symptoms and…

A gene called PSMC6 may be involved in driving inflammation and immune cell infiltration into the glands affected by primary Sjögren’s syndrome (pSS), a study found. PSMC6, which was more highly expressed, or active, in the blood of pSS patients than in that of healthy people, also was linked to lower…

Investigational therapy dazodalibep significantly eased symptom burden in people with Sjögren’s syndrome who have moderate-to-severe symptoms, but minimal systemic disease activity, meeting the goal of Horizon Therapeutics‘ Phase 2 clinical trial. Horizon previously announced the trial also met its other main goal of reducing disease activity in…

Polyphenols in rabbiteye blueberry leaves may help lower eye dryness in Sjögren’s syndrome, a mouse study suggests. “Blueberry leaves are foods that can be consumed daily, and we suggest that their intake may be useful in relieving the symptoms of lacrimal hyposecretion [low production and release] associated with Sjögren’s…

Women with Sjögren’s syndrome had early menopause more often, but didn’t have a higher rate of miscarriage compared with the general population, a study in a Chinese population shows. The study, “Menstrual and reproductive characteristics of patients with primary sjogren’s syndrome: a 7-year single-center retrospective study,” was published…

People who have a parent or sibling with an autoimmune disease are nearly six times as likely to develop primary Sjögren’s syndrome (pSS) than those who have no immediate family with such health issues, a meta-analysis study has found. Other risk factors for pSS include a history of pregnancy,…

People with primary Sjögren’s syndrome (PSS) are at an increased risk of developing heart failure, heart attack, stroke, and other cardiovascular health problems compared with the general population, a new study reports. “The findings from our analysis could potentially have important clinical implications,” the researchers wrote. “Despite a low…