News

Dry eye disease (DED) was found to significantly affect health- and vision-related quality of life in people with Sjögren’s syndrome in a new study. Patients with Sjögren’s “have a lower perceived [life quality] especially in relation to physical and mental wellbeing, correlating to severity of DED symptoms and…

A gene called PSMC6 may be involved in driving inflammation and immune cell infiltration into the glands affected by primary Sjögren’s syndrome (pSS), a study found. PSMC6, which was more highly expressed, or active, in the blood of pSS patients than in that of healthy people, also was linked to lower…

Investigational therapy dazodalibep significantly eased symptom burden in people with Sjögren’s syndrome who have moderate-to-severe symptoms, but minimal systemic disease activity, meeting the goal of Horizon Therapeutics‘ Phase 2 clinical trial. Horizon previously announced the trial also met its other main goal of reducing disease activity in…

Polyphenols in rabbiteye blueberry leaves may help lower eye dryness in Sjögren’s syndrome, a mouse study suggests. “Blueberry leaves are foods that can be consumed daily, and we suggest that their intake may be useful in relieving the symptoms of lacrimal hyposecretion [low production and release] associated with Sjögren’s…

Women with Sjögren’s syndrome had early menopause more often, but didn’t have a higher rate of miscarriage compared with the general population, a study in a Chinese population shows. The study, “Menstrual and reproductive characteristics of patients with primary sjogren’s syndrome: a 7-year single-center retrospective study,” was published…

People who have a parent or sibling with an autoimmune disease are nearly six times as likely to develop primary Sjögren’s syndrome (pSS) than those who have no immediate family with such health issues, a meta-analysis study has found. Other risk factors for pSS include a history of pregnancy,…

People with primary Sjögren’s syndrome (PSS) are at an increased risk of developing heart failure, heart attack, stroke, and other cardiovascular health problems compared with the general population, a new study reports. “The findings from our analysis could potentially have important clinical implications,” the researchers wrote. “Despite a low…

Vagus nerve stimulation (VNS), a procedure using a hand-held device to deliver electrical pulses to a nerve in the neck, eased fatigue for people with Sjögren’s syndrome in a small clinical trial. “Our data support further investigation into the role of [VNS] as a treatment for fatigue in patients with…

A 69-year-old woman in China was diagnosed with not one but two rare autoimmune diseases, according to researchers, who reported the case of Sjögren’s syndrome occurring alongside the skin disorder Lichen sclerosus as a reference for clinicians. “Given the rarity of such cases, we report this case to provide…

Sjögren’s syndrome is associated with a significantly increased risk of miscarriage and other adverse outcomes during pregnancy, a recent study reports. The study, “A meta-analysis of the effect of Sjögren’s syndrome on adverse pregnancy outcomes,” was published in the journal Clinics. Sjögren’s syndrome mainly affects…