News

Cyporin N, a new formulation of cyclosporin A, provides faster relief of chronic dry eye triggered by primary Sjögren’s syndrome than Restasis, results from a Phase 3 trial show. The study, “Evaluation of the Efficacy and Safety of A Novel 0.05% Cyclosporin A Topical Nanoemulsion in…

Researchers have found that by performing an easy interview about a patient’s pain, clinicians might be able to differentiate between small nerve fiber damage of unknown cause and that caused by Sjögren’s syndrome. Their study, “The Clinical Features of Painful Small-Fiber Neuropathy Suggesting an Origin Linked…

Sjögren’s syndrome patients are three times more likely to have thyroid disease, both autoimmune and non-autoimmune, than controls, a review of eight published studies shows. The study, “Increased risk of thyroid disease in patients with Sjogren’s syndrome: a systematic review and meta-analysis,” was published in PeerJ. Sjögren’s…

Advanz Pharma has acquired the global rights (except in Japan) to market Salagen (pilocarpine hydrochloride) tablets, an approved therapy for dry mouth in people with Sjogren’s syndrome, the company announced. Salagen, originally marketed by Eisai, is also used as a treatment for relieving dry mouth in head…

Aspirin-triggered resolvin D1 (AT-RvD1), a molecule that reduces tissue inflammation and promotes wound healing, restores the function of salivary glands and decreases the levels of immune T-helper 17 cells in a mouse model of  Sjögren’s syndrome, a study reports. The findings of the study, “Aspirin Triggered Resolvin…

The Hungarian regulatory authority has agreed to extend the label of Wize Pharma‘s LO2A eye drops to include the treatment of dry eye symptoms in Sjögren’s syndrome patients, the company announced. The treatment is marketed in Hungary as Conheal, by Resdevco. While the formulation is registered and marketed for the treatment of dry…

Those with Sjögren’s syndrome appear to be at higher risk for osteonecrosis of the jaw (ONJ), a condition where, after undergoing tooth extraction, a person’s jawbone is cut off from its blood supply and starts to starve, a study found. The study, “Increased risk of bisphosphonate-related osteonecrosis…

Madeline Collin, a 24-year-old activist with Gaucher disease, worries that patients like her will suffer deeply if Britain leaves the European Union (EU), as scheduled, at the end of this month. Collin is an expert on the subject. For her University of Bath dissertation, she analyzed Brexit’s long-term…

With each new advance in medicine comes ethical dilemmas, from fertility treatments and newborn screening, to vaccinations, gene therapies and euthanasia. But rare diseases and the expensive therapies needed to treat them — particularly in an age of scarce economic resources — almost always entail “tragic choices,” warned Avraham Steinberg,…

Rare diseases affect about 30 million Americans — roughly the same number as those with type 2 diabetes. Yet only 5 percent of the estimated 7,000 rare diseases known to science have cures or treatments approved by the U.S. Food and Drug Administration (FDA). Raising awareness of those illnesses and highlighting…