Author Archives: Inês Martins PhD

Bacteria in Mouth May Trigger Inflammation Damaging to Salivary Glands

Alterations in salivary glands that cause immune cell infiltration in Sjӧgren’s syndrome patients may be triggered by changes in the mouth’s bacterial composition, findings from a recent study suggest. While many bacterial changes were evident, one particular bacterial species was enough to initiate an inflammatory cascade that contributed in…

Vaginal Dryness and Pain Can Affect Sexual Intimacy in Primary Sjögren’s Patients, Study Finds

Difficulties with engaging in sex — including arousal, lubrication, orgasm, and satisfaction — are significant in women with primary Sjögren’s syndrome compared to healthy women, and sexual function decreases as disease duration increases, a study reports. The findings, “Primary Sjögren’s Syndrome Adversely Affects the Female Sexual Function Assessed by…

Leflunomide-Hydroxychloroquine Combo Shows Potential for Sjögren’s Patients in Pilot Trial

A combination of leflunomide and hydroxychloroquine significantly reduced disease activity, increased salivary flow, and improved patient-perceived health in patients with primary Sjögren’s syndrome, a pilot trial showed. Findings of the trial were revealed at the recent American College of Rheumatology 2018 Meeting, in Chicago. Timothy Radstake, MD, PhD, from the …