Tocilizumab, a medicine approved for certain types of arthritis, may be a safe and effective approach for treating severe respiratory distress associated with COVID-19 in people with autoimmune conditions, the case of an elderly Sjögren’s syndrome patient suggests. The report, “…
Use of oral pilocarpine increased salivary flow in people with dry mouth due to primary Sjögren’s syndrome or other health conditions in a small study. However, the medication did not significantly alter dental health or the structure of the salivary glands, as assessed via ultrasound. The study, “…
An international trial is recruiting people with Sjögren’s syndrome to investigate the feasibility of an online app, called Sjogo, that’s designed to support the self-management of symptoms. Recruitment is primarily being done via Twitter, the American microblogging and social networking service. The Sjogo app…
The Sjögren’s Foundation is recommending that people with Sjögren’s syndrome ages 16 and older be vaccinated against  COVID-19 infection, and advices patients to talk with their healthcare provider about potential decisions and vaccination timing. The recommendation, released online in a statement, was based on safety and effectiveness…
In-hospital mortality, the length of a hospital stay, and hospitalization charges for people with acute kidney injury and Sjögren’s syndrome are no different from those without Sjögren’s, a large-scale database analysis found. An interesting finding of the analysis was…
A technique that delivers low electric currents to stimulate specific parts of the brain can safely reduce fatigue in people with primary Sjogren’s syndrome (pSS), a pilot study has found. Transcranial direct-current stimulation (tDCS) also helped patients in the areas of…
People with Sjögren’s syndrome and other systemic autoimmune rheumatic diseases (SARDs) may be at a greater risk of severe complications from COVID-19 than people without these disorders, a study reports. Specifically, SARDs patients are more likely to develop venous thromboembolism (VTE), or blood clots in…
RSLV-132, an investigational treatment for autoimmune conditions, led to significant and clinically meaningful reductions in patient-reported fatigue in people with primary Sjögren’s syndrome, results from a Phase 2 clinical trial show.
Primary Sjogren’s syndrome (pSS) patients have less diversity in their gut microbiome — with less abundant beneficial bacteria but more abundant opportunistic bacteria with pro-inflammatory activity — compared with healthy people, a study suggests. Patients also had higher levels of pro-inflammatory immune signaling molecules, which were…
Applications for a next round of Sjögren’s Foundation research grants are being accepted from U.S. investigators working to better understand Sjögren’s syndrome, a chronic immune system disorder, and improve patients’ lives. The one-year grants are available to basic and clinical scientists who hold an advanced degree at a U.S.
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