The Sjögren’s Foundation is calling on runners and walkers to take part in its Team Sjögren’s Training Program for a virtual event that will take place Nov. 25–28. The event will help increase awareness about the autoimmune condition and raise funds for research and education, the foundation announced in…
The findings of a new study support the development of Incyte‘s parsaclisib as a potential therapy for Sjögren’s syndrome and other autoimmune diseases. Parsaclisib, an oral inhibitor of phosphatidylinositol 3-kinase (PI3K) delta, was found to ease the symptoms of Sjögren’s and other disorders in a study using mouse models.
Current studies investigating treatment strategies for children with Sjögren’s syndrome have poor quality evidence for the development of clinical recommendations, a recent study has found. As such, these children are still prescribed medication based on their doctors’ opinions, not on evidence-based treatment recommendations. “Future research is required to guide…
Rituximab safely and effectively treated sudden interstitial lung disease (ILD) in a 49-year-old man with undiagnosed primary Sjögren’s syndrome, a case study shows. This case adds to a growing number of reports and case series showing that rituximab lessens lung involvement in Sjögren’s patients, further supporting the usefulness…
People with obsessive-compulsive disorder, known as OCD, are at an increased risk — more than three times higher than those who don’t have the condition — of developing Sjögren’s syndrome, according to a population-based study in Taiwan. Additionally, among the general population, women and individuals ages 65 and…
From sharing inspirational stories to educating others, supporters are poised to mark World Sjögren’s Day, observed annually on July 23 to raise awareness about the disease. Awareness and education are crucial to increasing the recognition, diagnosis, understanding, and management of Sjögren’s syndrome, a chronic autoimmune disorder that predominantly affects…
A Chinese herbal medication called SS-1 can reduce inflammation and improve saliva flow, likely due to an inhibitory effect on dendritic cells — a component of the innate immune system, according to a recent study in a mouse model of Sjögren’s syndrome. The study, “Effect of…
The number of lymphocytes — a type of immune blood cell — in the salivary glands of the lip could help identify patients with Sjögren’s syndrome who are at increased risk for developing lymphoma, a new study has found. The study, “A biomarker for lymphoma development in Sjogren’s…
A new method for dividing people with primary Sjögren’s syndrome (pSS) into subgroups based on detailed molecular differences may help improve precision treatment for patients, a recent study suggests. The findings “have major implications for the treatment of pSS patients,” researchers wrote, as they could help unravel the causes…
A subset of immune cells, called CD4+CD8+ T-cells, is increased in the blood of patients with Sjögren’s syndrome, and their levels seem to correlate with lower disease activity, according to a small study. The findings suggest doctors could make use of those cells to track or even control how…
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