News

December 7, 2020December 7, 2020

Study Links Altered Gut Microbiome in Sjogren’s to Systemic Inflammation

News

Primary Sjogren’s syndrome (pSS) patients have less diversity in their gut microbiome — with less abundant beneficial bacteria but more abundant opportunistic bacteria with pro-inflammatory activity — compared with ... Read more

November 30, 2020November 30, 2020

Sjogren’s Foundation Welcomes Applications for 2021 Research Grants

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Applications for a next round of Sjögren’s Foundation research grants are being accepted from U.S. investigators working to better understand Sjögren’s syndrome, a chronic immune system disorder, and improve patients’ ... Read more

November 26, 2020November 25, 2020

New $100M Program Aims to Improve Diversity in Clinical Trials

News, syndicated

A new $100-million program aims to improve the diversity of participants in U.S. clinical trials with the ultimate goal of achieving better health outcomes and parity in care for underserved ... Read more

November 23, 2020November 23, 2020

Sjogren’s Burden Determined by Organ Involvement, Fatigue, Pain, Study Suggests

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Primary Sjögren’s syndrome (pSS) syndrome can be classified based on the extent of organ involvement, fatigue, and pain, with symptoms varying substantially from patient to patient, a new study ... Read more

November 16, 2020November 16, 2020

LO2A Drops Lessen Dry Eye Symptoms, Even Outperform Systane on Some Measures

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Wize Pharma‘s LO2A eye drops result in clinically meaningful improvements in dry eye signs and symptoms in people with Sjögren’s syndrome, topline results from an exploratory Phase 4 trial show. ... Read more

November 9, 2020November 9, 2020

Hydroxychloroquine Lowers Cardiovascular Risk in Sjögren’s Patients, Study Suggests

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Long-term use of hydroxychloroquine significantly lowers the risk of coronary artery disease, the most common form of heart disease, in people with Sjögren’s syndrome, a data study in Taiwan suggested. ... Read more

November 2, 2020November 2, 2020

Study Links Immune Regulatory Molecule NEAT1 to Primary Sjogren’s

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An immune regulatory molecule known as NEAT1 is produced at greater levels in the immune T-cells of people with primary Sjogren’s syndrome, and these levels seem to correlate with ... Read more

October 26, 2020October 26, 2020

Seletalisib Shows Trend Toward Easing Primary Sjögren’s in Phase 2 Trial

News

Using the PI3K-delta inhibitor seletalisib as an add-on to standard treatment showed a trend toward easing disease activity and dryness, and significantly lowered patient-reported fatigue in people with primary ... Read more

October 19, 2020October 19, 2020

$3.7M NIH Grant Will Support Research to Pinpoint Genes Associated With Sjögren’s

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The National Institute of Arthritis and Musculoskeletal and Skin Diseases, a part of the National Institutes of Health, has awarded a $3.7 million grant to advance studies investigating which genes ... Read more

October 12, 2020October 12, 2020

Endoscopic Irrigation Brings Long-term Oral Relief to Sjögren’s Patients in Trial

News

The use of sialendoscopy, an endoscopic tool to examine and treat the salivary glands, can be used to irrigate the major salivary glands with saline to increase salivation and lessen ... Read more