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August 19, 2020August 19, 2020

Unexplained Kidney, Neurological Problems, Fever Could Be Sjögren’s, Case Study Suggests

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Primary Sjögren’s syndrome (pSS) should be considered in children with unexplained kidney and neurological symptoms, and unexplained fever, a study suggests. In the study, “Nephrological disorders and neurological involvement ... Read more

August 12, 2020August 12, 2020

Saliva Levels of IL-6 Protein May Help in Diagnosing Primary Sjögren’s

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Measuring the protein IL-6 in saliva may aid in diagnosing primary Sjogren’s syndrome (pSS), a study reports. The study, “Association of salivary inflammatory biomarkers with primary Sjögren’s syndrome,” was published ... Read more

July 29, 2020July 29, 2020

Severe Dryness Symptoms Increase Risk of Cavities, Oral Candida, Study Finds

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Severe dryness symptoms increase the risk of developing tooth cavities and having oral Candida infection in people with Sjögren’s syndrome, a new study found. The study, “Sicca Symptoms, Oral Health Conditions, ... Read more

July 22, 2020July 31, 2020

Australian Partnership to Advance Technology to Treat Sjogren’s

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The University of Queensland’s technology transfer company, UniQuest, will partner with the biotechnology company CSL Limited to develop and commercialize the university’s antigen specific immune tolerance induction (ASITI) technology ... Read more

July 15, 2020July 15, 2020

Luminary Therapeutics, Case Western Team Up to Develop New CAR T-Cell Therapy

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Luminary Therapeutics will collaborate with researchers at Case Western Reserve University to develop a new form of CAR T-cell therapy that uses the B-cell activating factor (BAFF) target as ... Read more

July 1, 2020July 1, 2020

Researchers Discover Two Potential Biomarkers for Primary Sjögren’s Syndrome

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A new study has uncovered two potential biomarkers of primary Sjögren’s syndrome (pSS): progranulin (PGRN) and Oxford 40 ligand (OX40L). People with pSS have higher levels of these two proteins compared to healthy volunteers. The ... Read more

June 24, 2020June 24, 2020

Bcl-6 ‘Master Regulator’ Discovery Sheds Light on Autoimmune Diseases Such as Sjogren’s

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Researchers have discovered the mechanisms by which Bcl-6 — a protein that is considered a “master regulator” of the immune system — controls the activity of a subset of ... Read more

June 17, 2020June 17, 2020

B-cell Protein May Contribute to Development of Primary Sjogren’s Syndrome, Study Suggests

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People with primary Sjögren’s syndrome (pSS) have significantly higher levels of CD72 — a regulatory protein on B-cells, a type of immune cell associated with pSS — than healthy peers, according to ... Read more

June 3, 2020June 3, 2020

Wize Completes Phase 4 Study of LO2A Eye Drops for Sjögren’s; Results Expected Later This Year

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A Phase 4 clinical trial evaluating Wize Pharma‘s LO2A eye drops as a treatment for dry eye symptoms in people with Sjögren’s syndrome has been completed, the company announced. Results ... Read more

May 20, 2020May 21, 2020

Researchers Shed Light on Genetics Behind Sex-based Vulnerability to Sjögren’s, Other Diseases

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Genetic variations in the complement system — a part of the immune response — contribute to differences between men and women in their susceptibility to Sjögren’s syndrome, lupus, and ... Read more

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