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January 15, 2019

Seletalisib Seen to Aid Saliva Production, Lower Inflammation in Mouse Study

News

The PI3K-delta inhibitor known as seletalisib, an investigative treatment for primary Sjögren’s syndrome, improved the production of saliva, lowered the levels of autoantibodies and inflammatory mediators, and decreased immune B- ... Read more

January 8, 2019January 8, 2019

Quick and Non-invasive Imaging Tool May Help to Diagnose Sjögren’s, Study Reports

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Sonoelastography, a fast and non-invasive imaging technique that detects increases in tissue rigidity in salivary glands, may help to diagnosis of primary Sjögren’s syndrome, a study suggests. The study, ... Read more

December 21, 2018December 21, 2018

Rising Healthcare Costs Strain EU Budgets Even as New Therapies Flourish

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Cash-strapped governments across the 28-member European Union are struggling to control runaway healthcare expenditures — at exactly the same time as the promise of new but expensive therapies to ... Read more

December 13, 2018

Sjogren’s, Lupus Patients Share Gut Microbiota Composition, Study Shows

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Patients with primary Sjogren’s syndrome (pSS) and systemic lupus erythematosus (SLE) share their gut microbial composition, which is different from the general population. Oral microbial composition, however, in different in ... Read more

December 6, 2018December 6, 2018

Vaginal Dryness and Pain Can Affect Sexual Intimacy in Primary Sjögren’s Patients, Study Finds

News

Difficulties with engaging in sex — including arousal, lubrication, orgasm, and satisfaction — are significant in women with primary Sjögren’s syndrome compared to healthy women, and sexual function decreases as disease ... Read more

November 29, 2018December 3, 2018

Leflunomide-Hydroxychloroquine Combo Shows Potential for Sjögren’s Patients in Pilot Trial

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A combination of leflunomide and hydroxychloroquine significantly reduced disease activity, increased salivary flow, and improved patient-perceived health in patients with primary Sjögren’s syndrome, a pilot trial showed. Findings of the trial ... Read more

November 15, 2018

Lip Biopsy a Sensitive Diagnostic Tool for Sjögren’s Syndrome, Study Reports

News

Lip biopsy increases the sensitivity of Sjögren’s syndrome diagnosis and is a key measure in the widely accepted diagnostic criteria, according to a multicenter Argentinian study. Findings of the study ... Read more

November 8, 2018

MeiraGTx Acquires Rights to AAV-AQP1 Gene Therapy for Sjögren’s Syndrome

News

MeiraGTx recently acquired global rights over an investigational gene therapy called AAV-AQP1 being developed to treat the excessive dry mouth and eyes experienced by patients with Sjögren’s syndrome. The announcement comes after ... Read more

November 1, 2018

Study Finds 5 Potential Biomarkers for Assessing Severity of Dry Eye Symptoms in pSS Patients

News

High levels of five proteins in tears correlate with the severity of dry eye signs in patients with primary Sjögren’s syndrome, implicating a role for these proteins in the ... Read more

October 30, 2018October 29, 2018

#NORDSummit – Major Issues on Table for Rare Disease Patients in US as Midterm Elections Approach

News

With the U.S. midterm elections now less than two weeks away, patient advocacy groups are solidly focused on a range of hot-button issues, from the Orphan Drug Tax Credit ... Read more

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