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July 15, 2020July 15, 2020

Luminary Therapeutics, Case Western Team Up to Develop New CAR T-Cell Therapy

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Luminary Therapeutics will collaborate with researchers at Case Western Reserve University to develop a new form of CAR T-cell therapy that uses the B-cell activating factor (BAFF) target as ... Read more

July 1, 2020July 1, 2020

Researchers Discover Two Potential Biomarkers for Primary Sjögren’s Syndrome

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A new study has uncovered two potential biomarkers of primary Sjögren’s syndrome (pSS): progranulin (PGRN) and Oxford 40 ligand (OX40L). People with pSS have higher levels of these two proteins compared to healthy volunteers. The ... Read more

June 24, 2020June 24, 2020

Bcl-6 ‘Master Regulator’ Discovery Sheds Light on Autoimmune Diseases Such as Sjogren’s

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Researchers have discovered the mechanisms by which Bcl-6 — a protein that is considered a “master regulator” of the immune system — controls the activity of a subset of ... Read more

June 17, 2020June 17, 2020

B-cell Protein May Contribute to Development of Primary Sjogren’s Syndrome, Study Suggests

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People with primary Sjögren’s syndrome (pSS) have significantly higher levels of CD72 — a regulatory protein on B-cells, a type of immune cell associated with pSS — than healthy peers, according to ... Read more

June 3, 2020June 3, 2020

Wize Completes Phase 4 Study of LO2A Eye Drops for Sjögren’s; Results Expected Later This Year

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A Phase 4 clinical trial evaluating Wize Pharma‘s LO2A eye drops as a treatment for dry eye symptoms in people with Sjögren’s syndrome has been completed, the company announced. Results ... Read more

May 20, 2020May 21, 2020

Researchers Shed Light on Genetics Behind Sex-based Vulnerability to Sjögren’s, Other Diseases

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Genetic variations in the complement system — a part of the immune response — contribute to differences between men and women in their susceptibility to Sjögren’s syndrome, lupus, and ... Read more

May 13, 2020May 13, 2020

Research Implicates MicroRNA in Primary Sjögren’s Syndrome Eye Inflammation

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A small RNA molecule may help to drive inflammation in the eyes of people with primary Sjögren’s syndrome (pSS), a new study reports. The findings imply that this molecule, ... Read more

May 6, 2020May 6, 2020

Damage to Eye Surface Evident in Sjögren Patients, Study Reports

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In addition to dry eyes, people with Sjögren syndrome have damage to the surface of their eyes, and those with most extensive damage have high levels of biomarkers linked ... Read more

April 29, 2020April 29, 2020

Surge in Telemedicine One ‘Good’ Outcome from COVID-19 Crisis, Doctors Say

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While there are few silver linings to the cloud created by COVID-19, the pandemic that has killed tens of thousands, hobbled economies worldwide and drove millions to quarantine in ... Read more

April 22, 2020April 22, 2020

Bacteria in Mouth May Trigger Inflammation Damaging to Salivary Glands

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Alterations in salivary glands that cause immune cell infiltration in Sjӧgren’s syndrome patients may be triggered by changes in the mouth’s bacterial composition, findings from a recent study suggest. ... Read more

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