People with Sjögren’s disease, especially younger patients, have more infections and more repeat infections than their healthy peers, according to a study that analyzed medical records. Most infections were recorded after a Sjögren’s diagnosis, which “may reflect immunologic shifts associated with the onset of SjD [Sjögren’s disease], utilization…
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Blood levels of several molecules involved in promoting or dampening inflammation may help distinguish people with Sjögren’s disease from healthy individuals and offer clues about disease activity and gland involvement, according to a small study. People with Sjögren’s showed significantly higher blood levels of the pro-inflammatory molecules IL-15, MCP-1,…
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About five out of every 100 people with Sjögren’s disease may experience serious cardiovascular events over nearly 10 years of follow-up, and these events are linked to a higher risk of death of any cause, a study in Spain shows. In addition to traditional cardiovascular risk factors, disease-specific factors…
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More than half of people with Sjögren’s disease have high levels of an inflammatory protein called interferon-alpha (IFN-alpha) and a distinct pattern of immune system dysregulation, according to data from people living in the U.K. Study findings suggest that IFN-alpha may be a critical marker to distinguish between different…
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