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The activity of certain “clock genes” — those involved in the body’s internal clock, or circadian rhythm — is significantly dysregulated in the salivary glands of people with primary Sjögren’s syndrome (pSS) and a disease mouse model, a study shows. Treatment with melatonin, a hormone that regulates the circadian…
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People with Sjögren’s syndrome may be at a higher risk of developing multiple types of cancer, according to a recent meta-analysis of several published studies. The analysis confirms a previously identified link between Sjögren’s and a type of blood cancer called non-Hodgkin lymphoma. It also highlighted new relationships between the…
A research team in Japan has developed three-dimensional (3D) “mini organs” from human stem cells to model the lacrimal glands, or tear ducts, which are dysfunctional in Sjögren’s syndrome. The first of their kind, these new mini organs, or organoids, can be used in the future to study disease…
Though she’s felt agitated recently, columnist Rena Newman is trying to walk in forgiveness and find peace amid her health issues.
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