Trinity Biotech, which specializes in diagnostic test kits, is partnering with the University at Buffalo, New York (UB) to develop and commercialize new testing strategies to improve the detection of Sjögren’s disease and aid in its diagnosis. “Sjögren’s is a significantly underdiagnosed condition that imposes a major burden…
People with primary Sjögren’s disease, particularly those with more severe illness, show significantly different patterns of alternative splicing — a process in which cells mix and match gene instructions to create different versions of a protein — in 10 genes compared with healthy people, according to a study in China.
Initial data from an early clinical trial testing CLN-978, Cullinan Therapeutics’ experimental therapy, in adults with moderate to severe Sjögren’s disease are expected in the final months of the year. The announcement was part of a company press release providing the latest financial results and corporate updates.
Adults with primary Sjögren’s disease are at a higher risk of developing colorectal and pancreatic cancers — especially women and older patients — according to a Korean study. “Further research should explore the underlying mechanisms and the impact of [primary Sjögren’s disease] duration and severity on cancer risk,” researchers…
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