A woman with Sjögren’s disease was the first to receive an experimental cell therapy for xerostomia, or severe dry mouth, in a clinical trial at the University of Wisconsin (UW). As part of the Phase 1 study (NCT06392711), six patients are receiving one injection of their own mesenchymal…
It’s a stale Saturday night and I’m in my living room hanging with the kitties. My eyes are devastatingly dry and irritatingly itchy! I rub my left eye with two fingers and then my right, which is itchier and burns more for some reason. Of course, I can’t get in there good enough since my fingers are weak and sensitive,…
Use of oral pilocarpine increased salivary flow in people with dry mouth due to primary Sjögren’s syndrome or other health conditions in a small study. However, the medication did not significantly alter dental health or the structure of the salivary glands, as assessed via ultrasound. The study, “…
The hormone adiponectin correlates with disease severity in Sjogren’s syndrome patients, and could be used as a salivary biomarker to diagnose the disease, a Spanish pilot study shows. The research, “Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren’s syndrome: a pilot study,” was…
Pilocarpine is an effective treatment for mouth and eye dryness in patients with Sjogren’s syndrome, a Phase 4 trial from Chile showed. The trial compared the medicine to artificial saliva for 12 weeks in patients with primary and secondary Sjogren’s syndrome. At the end of the study, most patients in the…
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