News

Levels of the chemical messenger CCL28 are reduced in the blood of people with primary and secondary Sjögren’s syndrome, and were correlated with oral disease features like dental cavities and salivary gland damage, according to a recent Chinese study. Additionally, blood count changes — also lower — were linked…

Intense pulsed light therapy along with meibomian gland expression (IPL-MGX) significantly eased dry eye symptoms and improved eye health in people with Sjögren’s syndrome, according to a recent study.  “Our results indicated that three IPL-MGX sessions could significantly improve the subjective and objective…

NYU Langone Health is joining with a National Institutes of Health (NIH) sponsored program aimed at understanding disease mechanisms and developing new treatments for autoimmune disorders such as Sjögren’s syndrome. The program, called Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases (AMP AIM), began last year in an…

This year’s Sjögren’s Awareness Month will focus on patient experiences to share glimpses into the lives of people with Sjögren’s syndrome, a complex disorder that is thought to affect four million U.S. residents. Each day in April, the Sjögren’s Foundation will showcase a different patient on its website and…

The thickness of the eye’s retina and the density of retinal blood vessels are significantly lower in women with Sjögren’s syndrome than healthy women, an imaging study demonstrated. Retinal thinning, as measured by the noninvasive imaging technique called optical coherence tomography angiography (OCTA), may help diagnose Sjögren’s, according to…

Fatigue had the biggest impact on daily activities among people with primary Sjögren’s syndrome and was one of a number of symptoms associated with increased anxiety, depression, and physical limitations, according to a recent U.K. study. This effect was markedly reduced in patients with a longer disease duration, suggesting that…

Dry eye disease is more severe in people with primary Sjögren’s syndrome than in other patients, but their perception of eye discomfort may be altered, according to a recent study. “Clinicians should be aware that [Sjögren’s] patients may complain less of their discomfort” while having a particularly severe case…

Hospitalized patients with primary Sjögren’s syndrome (pSS) show an increased rate of specific cardiovascular concerns and sleep apnea syndrome (SAS), according to a study of a nationwide health insurance database in France. The cardiovascular issues include ischemic heart disease (heart disease associated with narrowed blood vessels) and pulmonary hypertension…

No connection is evident between exposure to the dental amalgam used to fill cavities and the risk of developing Sjögren’s syndrome,  a study by researchers in Taiwan reported. The study, “Analysis of dental amalgam fillings on primary Sjögren’s syndrome,” was published in Medicine.  Dental amalgam is…

A first patient has enrolled in a Phase 3 trial evaluating cenegermin in treating dry eye disease in people with Sjögren’s syndrome, marking the start of a two-part clinical study program, Dompé, the therapy’s developer, announced. The program will evaluate the safety and efficacy of…