News

Poor sleep quality is linked to both fatigue and increased disease activity in primary Sjögren’s syndrome patients, a study reported. Its researchers recommend more study into ways that might help patients with difficulty sleeping, a common problem in this disease. The study, “Correlation of sleep quality with fatigue and disease activity…

People with primary Sjögren’s syndrome who have symptoms outside their glands may carry a higher risk of developing other conditions, such as heart or thyroid disease, and might also be more prone to fractures, according to a study. The findings suggest that making the evaluation of these additional conditions…

The immune cells that produce self-targeting antibodies in cryoglobulinemia vasculitis (CV), a complication of Sjogren’s syndrome, are characterized by mutations that are known to drive lymphomas, a new study suggests. This finding provides clues as to how autoimmune diseases develop, and could open new avenues for diagnosis…

People with primary Sjögren’s syndrome have poor overall and oral health-related quality of life compared to healthy people, but these measures appear to be even worse among those with dryness symptoms (sicca) not related to the disorder, a study has found. The findings suggest that people with non-Sjögren’s…

In recognition of Rare Disease Day Feb. 29, Bionews Services launched a social media campaign last month asking patients to describe what makes them rare. Running Feb. 7–29, the #WhatMakesMeRare campaign was aimed at uplifting people with rare diseases by encouraging them to share their stories and perspectives. The…

Catalpol, the active ingredient in a medicinal herb often used for Sjögren’s syndrome treatment, eases disease symptoms by altering the balance and communication of specific immune cells, a study in mice suggests. The study, “Catalpol ameliorates Sjögren’s Syndrome by modulating interplay of T and B cells,”…

Iscalimab, an investigational antibody therapy from Novartis, showed promise for safety and preliminary efficacy for lessening disease activity in people with primary Sjögren’s syndrome who experience symptoms across the body. Larger and longer studies are warranted to assess the clinically meaningful benefits of the potential therapy, researchers…

Doctors should consider a diagnosis of primary Sjogren’s syndrome when faced with adolescent patients who show psychotic symptoms such as suicidal thoughts, auditory hallucinations, and paranoia, according to a case series. Titled “Adolescent Sjogren’s syndrome presenting as psychosis: a case series,” the report…

Patients with Sjögren’s syndrome and Behçet’s disease have a significantly higher risk of developing obstructive sleep apnea compared to people without those autoimmune disorders, a study has found. The study, “Risk of Obstructive Sleep Apnea in Patients with Sjögren Syndrome and Behçet’s Disease: A Nationwide, Population-Based…

The U.S. Food and Drug Administration (FDA), a vast government bureaucracy, employs about 17,500 people and had a budget of $5.7 billion in 2019. Yet even with its enormous resources, the FDA these days relies more and more on patients to…