News

Doctors should suspect primary Sjögren’s syndrome when examining patients, especially young women, with recurrent aseptic meningitis — a form of inflammation of the meninges, a membrane protecting the brain and spinal cord, that is not caused by bacteria, a case report suggests. The study, “Recurrent aseptic meningitis:…

Interstitial lung disease (ILD), or lung tissue scarring, commonly occurs in people with primary Sjögren’s syndrome in China and significantly burdens their quality of life, in particular their physical capacity, a Chinese study reports. Strengthening early interventions and treatment is of great importance in preventing ILD and improving…

Immunoglobulin injections may be a good choice to help resolve damage to the nerves that provide sensation or underly movement — a condition called peripheral neuropathy — in patients with Sjögren’s syndrome, a review…

New diagnostic criteria for systemic lupus erythematosus (SLE), released by the European and American rheumatology societies, helps to better distinguish patients with lupus from those with primary Sjögren’s syndrome, a study reports. The study, “New 2019 SLE EULAR/ACR classification criteria are valuable for distinguishing patients with SLE…

The content of mesenchymal stem cells — cells that can make several cell types, including cartilage and bone — improved saliva and tear flow, increased tissue regeneration, and reduced immune cell infiltration and autoantibody production in a mouse model of Sjogren’s syndrome, a study found. The study, “…

Artificial intelligence may complement — or even replace — manual search for researchers performing literature reviews, a new study suggests. The study, which used primary Sjögren’s syndrome as an example, also points out a need for more research on how the condition affects the skin. The study, “…

Oral rebamipide, a gastroprotective medication approved in some countries, may slow the progression of Sjögren’s syndrome by increasing the number of regulatory B- and T-cells and reducing the production of inflammatory molecules in the salivary glands and spleen, according to research in a mouse model of the disease. The study,…

Next month’s annual conference of the National Organization for Rare Disorders (NORD) in Washington, D.C., couldn’t come at a better time, says Marshall Summar, MD, chairman of NORD’s board of directors. “The pace of discovery in rare diseases has gone from brisk to hypersonic,” Summar told Bionews Services, publisher…

A study in Korean patients found five new gene variants associated with the development of Sjögren’s syndrome, which may provide biomarkers for precision medicine, the scientists said. The research, “Variants at potential loci associated with Sjogren’s syndrome in Koreans: A genetic association study,” appeared in the journal…

A non-invasive assessment of salivary gland damage by ultrasound may be added to current criteria for primary Sjögren’s syndrome (pSS) diagnosis without lowering their accuracy, according to a large clinical practice study. The inexpensive assessment may replace invasive tests that are unavailable in some centers, which improves the feasibility…