News

Men with Sjögren’s may be at higher pulmonary hypertension risk

Men with Sjögren’s disease show more early signs of lung and heart dysfunction than women and may be at an increased risk of developing pulmonary hypertension, a cardiovascular complication of Sjögren’s, a study reports. “As male patients demonstrated a greater predisposition to developing [pulmonary hypertension] … regular echocardiographic…

MicroRNA may be therapeutic target for Sjögren’s: Study

A naturally occurring molecule that has the ability to regulate gene activity may represent a promising therapeutic target for Sjögren’s disease and other autoimmune conditions, according to a study. Mimicking the activity of the molecule, miR-216a-3p, eased inflammation and scarring in a rat model of the disease. Its therapeutic…

Salivary gland ultrasound may assess primary Sjögren’s activity

More severe salivary gland damage and lymph node enlargement detected by ultrasound examination are associated with higher disease activity in primary Sjögren’s disease, a study in South Korea reports. Also, researchers found that more severe salivary gland damage was tied to a higher prevalence of laboratory risk factors for…

Sexual dysfunction affects nearly 80% of women with Sjögren’s

Nearly 80% of women with Sjögren’s disease experience sexual dysfunction, with common symptoms including vaginal dryness, lower sexual satisfaction, and difficulty with arousal, a Chinese study finds. The findings highlight the need of “increased awareness and recognition of sexual health in clinical practice,” the researchers wrote, adding that “policymakers…