Primary Sjogren’s syndrome (pSS) patients have less diversity in their gut microbiome — with less abundant beneficial bacteria but more abundant opportunistic bacteria with pro-inflammatory activity — compared with healthy people, a study suggests. Patients also had higher levels of pro-inflammatory immune signaling molecules, which were…
An immune regulatory molecule known as NEAT1 is produced at greater levels in the immune T-cells of people with primary Sjogren’s syndrome, and these levels seem to correlate with disease duration, a study has found. The findings suggest that NEAT1 may be used as a new…
The use of sialendoscopy, an endoscopic tool to examine and treat the salivary glands, can be used to irrigate the major salivary glands with saline to increase salivation and lessen oral dryness in people with Sjögren’s syndrome, with benefits…
High activity levels in immune-related genes are associated with the malfunction of immune cells isolated from people with primary Sjogren’s syndrome, a small study revealed. Such increased gene activity levels correlate with disease severity, the researchers found. Titled “…
In addition to dry eyes, people with Sjögren syndrome have damage to the surface of their eyes, and those with most extensive damage have high levels of biomarkers linked to inflammation, a study found. People whose syndrome is related to…
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