Alice Melao,  —

Patients with primary Sjögren’s syndrome whose first symptoms are not mouth and eye dryness may experience more progressive and severe pulmonary manifestations during the course of their disease, a study reports. The study, “Interstitial lung disease in non-sicca onset primary Sjögren’s syndrome: a large-scale case-control study,” appeared…

Severe muscle weakness in all four limbs may be a symptom of Sjögren’s syndrome, a case report contends. Researchers hope their study will increase awareness about the multitude of ways Sjögren’s syndrome may be recognized, and subsequently improving the diagnosis. The study, “Complete Hypokalemic Quadriparesis as a…

Adding supplements of epidermal growth factor — a signaling protein — to the current treatment regimens of Sjögren’s syndrome, may improve oral damage and quality of life in patients with the disease, a new study suggests. The study, “Deterioration in saliva quality in patients with Sjögren’s syndrome: impact of decrease…

Blocking the signals from interleukin-7 (IL-7) — a protein involved in T-cell development and normal functioning — reduces the clinical manifestations of Sjögren’s syndrome in mice, research shows. These findings suggest that IL-7 and its receptor are important contributors for the autoimmune response in Sjögren’s syndrome, and could represent…

ImmunoQure and Servier have joined efforts to develop a new therapeutic antibody that could benefit patients with Sjögren’s syndrome and systemic lupus erythemathosus. The antibodies will be targeting interferon-alpha (INF-α), a protein needed for immune responses against invading pathogens. Interferon alpha is produced at high levels in…