Cerebellar atrophy — the deterioration of nerve cells in the cerebellum — is a rare but serious manifestation of primary Sjogren’s syndrome, according to a new case study from Iran. The report, “Cerebellar degeneration in primary Sjogren syndrome,” was published in the journal BMJ Case Reports. Sjogren’s…
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Patients with primary Sjogren’s syndrome (pSS) show altered levels of specific types of immune T-cells and B-cells, which may play an important role in disease activity, new research from Norway suggests. The study, “T follicular-like helper cells in the peripheral blood of patients with primary Sjogren’s…
Although rare, localized amyloidosis can sometimes appear as a consequence of Sjogren’s syndrome, according to a case report from South Korea. The study, “Primary Sjogren syndrome diagnosed simultaneously with localized amyloidosis of the lacrimal gland: A case report,” was published in the journal Medicine. A 45-year-old woman arrived at Pusan National University…
Treatment with interferon-beta (IFN-β) reduces the inflammatory response in immune cells from Sjögren’s syndrome patients, a study reports. The findings suggest that treatment with IFN-β may be a potential way of controlling inflammation in Sjögren’s patients. The study, “…
Yeast colonization in the oral cavity of patients with Sjogren’s syndrome follows a different pattern compared to healthy people, suggesting a reason why some patients respond better to commonly prescribed antifungal agents compared with others, a new study shows. The study, “Oral yeast colonization in patients with…
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Oral Health of Primary Sjögren’s Patients Seen as Similar to That of Healthy Controls in Small Study
The oral health of patients with primary Sjögren’s syndrome is similar to that of patients with rheumatoid arthritis or healthy individuals, a small study suggests. The study, “Clinical periodontal status and inflammatory cytokines in primary sjogren syndrome and rheumatoid artritis,” was published in The Journal of Periodontology. Primary Sjögren’s…
As President Trump signed the recently passed Right to Try legislation into law in a White House ceremony, Jordan McLinn of Indianapolis tried twice to embrace him. The third time, 9-year-old Jordan finally got the hug he wanted — as well as a kiss on the forehead. The video of…
Use of big data machine learning to study autoimmune diseases is on the rise, but little focus has been devoted to primary Sjogren’s syndrome (pSS), a French study reports. The study, “Pathogenesis-based treatments in primary Sjogren’s syndrome using artificial intelligence and advanced machine learning techniques: a…
Finding treatments and potential cures for rare diseases is crucial, but so is the quality of patients’ lives — a rather nebulous term that means different things to different people. “Recently, there’s been much more of a focus on Quality of Life (QoL) issues, real-world evidence and patient-reported outcomes,” said…
LO2A eye drops significantly improve dry eye symptoms in Sjögren’s syndrome patients, according to a small Phase 2 clinical study performed in Hungary. The findings were presented at the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, on May 2 in Honolulu, Hawaii, in the poster presentation “…
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