Patricia Inácio, PhD, science writer —

American Indians are more commonly affected by Sjögren’s syndrome and show more active disease compared to Americans of other ethnicities, a study shows. The study, “American Indians Have A Higher Risk Of Sjögren’s Syndrome And More Disease Activity Than Caucasians And African-Americans,” was published in the journal…

Advanz Pharma has acquired the global rights (except in Japan) to market Salagen (pilocarpine hydrochloride) tablets, an approved therapy for dry mouth in people with Sjogren’s syndrome, the company announced. Salagen, originally marketed by Eisai, is also used as a treatment for relieving dry mouth in head…

The Hungarian regulatory authority has agreed to extend the label of Wize Pharma‘s LO2A eye drops to include the treatment of dry eye symptoms in Sjögren’s syndrome patients, the company announced. The treatment is marketed in Hungary as Conheal, by Resdevco. While the formulation is registered and marketed for the treatment of dry…

Lower levels of Gαq — a protein that regulates many aspects of immune responses — appear to drive the progression of primary Sjogren’s syndrome by increasing a subset of pro-inflammatory immune cells, a study shows.  The study, “Expression of Gαq Is Decreased in Lymphocytes from Primary Sjogren’s Syndrome…

Although rare, localized amyloidosis can sometimes appear as a consequence of Sjogren’s syndrome, according to a case report from South Korea. The study, “Primary Sjogren syndrome diagnosed simultaneously with localized amyloidosis of the lacrimal gland: A case report,” was published in the journal Medicine. A 45-year-old woman arrived at Pusan National University…

The oral health of patients with primary Sjögren’s syndrome is similar to that of patients with rheumatoid arthritis or healthy individuals, a small study suggests. The study, “Clinical periodontal status and inflammatory cytokines in primary sjogren syndrome and rheumatoid artritis,” was published in The Journal of Periodontology. Primary Sjögren’s…

Patients with primary Sjögren’s syndrome and joint inflammation are significantly more likely to have severe or very severe dry eye, according to a multi-center study in Spain. The finding suggests a potential new strategy to identify signs of the disease that may lead to early treatment. The study, “Factors associated…

Sleep problems are common in primary Sjogren’s syndrome patients and seem to worsen symptoms of fatigue and pain, affecting the ability of patients to perform daily activities, according to researchers from the U.K. But a focus group study reports Sjogren’s patients are generally open to tailored sleep therapy interventions as…

In rare cases, patients with Sjögren’s syndrome may develop an unusual degradation of the kidney’s filtering system — a condition called fibrillary glomerulonephritis — a case report shows. While this is only the third case describing this association, the study adds Sjögren’s to the list of disorders linked to fibrillary…

Wize Pharma has enrolled the first participant in a Phase 4 clinical trial investigating the company’s LO2A drops to prevent the dry eye seen in Sjogren’s syndrome. The trial (NCT03319420) in Israel will compare LO2A’s ability to relieve dry eyes with that of an over-the-counter treatment known as Systane…