Iqra Mumal, MSc,  —

Poor sleep quality is linked to both fatigue and increased disease activity in primary Sjögren’s syndrome patients, a study reported. Its researchers recommend more study into ways that might help patients with difficulty sleeping, a common problem in this disease. The study, “Correlation of sleep quality with fatigue and disease activity…

People with primary Sjögren’s syndrome who have symptoms outside their glands may carry a higher risk of developing other conditions, such as heart or thyroid disease, and might also be more prone to fractures, according to a study. The findings suggest that making the evaluation of these additional conditions…

People with Sjögren’s syndrome — particularly women, younger patients and those receiving certain immunosuppressant therapies — are at higher risk of developing Parkinson’s disease, according to a new study. The study, “Risk of Parkinson disease in Sjögren syndrome administered ineffective immunosuppressant therapies,” was published in the journal Medicine. Recently, studies have…

Pain, depression, and daytime sleepiness are significantly associated with both mental and physical fatigue in patients with primary Sjögren’s syndrome, even after adjusting for comorbidities and medication, a new study shows. Management of fatigue in these patients should thus be tailored to each patient, depending on potential contributors, and focused…

Dental implants are a viable option for people with Sjogren’s syndrome, but these patients may experience a higher marginal bone loss around their implants than patients from the general population, a study shows. The study, “Dental implants in patients with Sjogren’s syndrome: a case series and a systematic review,”…

High levels of five proteins in tears correlate with the severity of dry eye signs in patients with primary Sjögren’s syndrome, implicating a role for these proteins in the disease, a study shows. The study, “Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients…

While rare, patients with primary Sjogren’s syndrome can develop central nervous system disease due to involvement of large blood vessels, rather than small or medium-sized blood vessels, according to a new case study. The study, “Cerebral Large-Vessel Vasculitis in Sjogren’s Syndrome: Utility of High-Resolution Magnetic Resonance Vessel Wall Imaging,”…

Levels of migration inhibitory factor (MIF), a pro-inflammatory immune molecule, are significantly higher in the serum of patients with primary Sjogren’s syndrome, suggesting it could play a part in diagnosing the disease. MIF levels, however, do not correlate with any clinical characteristics and additional studies are needed to understand…

A subtype of rheumatoid factor targeting a class of antibody called immunoglobulin A can be used as a diagnostic and predictive marker for primary Sjogren’s syndrome, a new study shows. The study, “Clinical and diagnostic significance of serum immunoglobulin A rheumatoid factor in primary Sjogren’s syndrome,” was published in…

Individuals with dry mouth, including those with Sjögren syndrome, may benefit from using a moisturizing mouthwash with cetylpyridinium chloride, a new study shows. The study, “A randomized controlled study to evaluate an experimental moisturizing mouthwash formulation in participants experiencing dry mouth symptoms,” was published in the journal Oral Surgery, Oral…