David Melamed,  —

Researchers Discover Two Potential Biomarkers for Primary Sjögren’s Syndrome

A new study has uncovered two potential biomarkers of primary Sjögren’s syndrome (pSS): progranulin (PGRN) and Oxford 40 ligand (OX40L). People with pSS have higher levels of these two proteins compared to healthy volunteers. The study, “Clinical Significance of Progranulin Correlated With Serum Soluble Oxford 40 Ligand in Primary Sjögren’s…

Catalpol Improves Sjogren’s Symptoms by Affecting Immune Cell Interactions, Mouse Study Suggests

Catalpol, the active ingredient in a medicinal herb often used for Sjögren’s syndrome treatment, eases disease symptoms by altering the balance and communication of specific immune cells, a study in mice suggests. The study, “Catalpol ameliorates Sjögren’s Syndrome by modulating interplay of T and B cells,”…