Note: This story was updated Oct. 1, 2024, to clarify that Sjögren’s is a systemic disease, meaning it can affect moisture-producing glands, as well as other parts of the body. Ainos is planning to launch a Phase 3 clinical trial in Taiwan before the year’s end to evaluate the…
Lip salivary gland biopsy using an auxiliary device called chalazion forceps may diagnose primary Sjögren’s disease as accurately as the conventional method, but with fewer procedure-related complications, a study suggests. Researchers noted that, compared with the conventional method, “the modified [lip salivary gland biopsy] … offers a good safety…
Women with primary Sjögren’s syndrome are more likely to give birth prematurely and have babies born with congenital heart block (CHB) — a condition that disrupts the transmission of electrical signals within the heart needed to maintain a normal heartbeat — than women with other autoimmune conditions, a study…
Lip salivary gland biopsy may not be predictive of a Sjögren’s syndrome diagnosis, particularly when it’s based on tissue samples classified as showing a low level of inflammation and damage, according to a study. In 16% of the cases assessed in the study, different pathology teams would draw different conclusions…
World Sjögren’s Day is held every July 23, the birthday of Henrik Sjögren, the Swedish ophthalmologist who first identified Sjögren’s syndrome in 1933, and this year, to observe the 40th anniversary of the Sjögren’s Foundation, Amgen has pledged a dollar-to-dollar match up to $40,000, meaning donations supporting…
A new photo-detection method was able to accurately and quantitatively measure lactoferrin levels in the tears of people with dry eye disease (DED) associated with Sjögren’s syndrome or other conditions, a study shows. The method also let researchers distinguish patients with DED caused by Sjögren’s from other DED…
Introducing immunosuppressive or biological therapies early in people with Sjögren’s syndrome may prevent its progression to a bodywide systemic condition, a study in France suggests. “In our study, we can see that the introduction of [immunosuppressive agents] or biotherapy in systemic forms is only effective in around 50% of…
Patients with primary Sjögren’s syndrome who have extra-glandular symptoms have higher levels of the chemokine CXCL9 than those only affected in the saliva and tear-producing glands, a study finds. CXCL9 is a small signaling molecule involved in the migration and maturation of lymphocytes, a type of immune cell thought…
People with primary Sjögren’s syndrome who’d never received treatment for it show disturbances in their gut microbiota similar to what’s seen in systemic lupus erythematosus (SLE), another chronic autoimmune disorder, a study in China reports. Gut microbiota are microorganisms in the gastrointestinal tract — bacteria, fungi, and viruses —…
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