Andrea Lobo, PhD, science writer —

A new photo-detection method was able to accurately and quantitatively measure lactoferrin levels in the tears of people with dry eye disease (DED) associated with Sjögren’s syndrome or other conditions,  a study shows. The method also let researchers distinguish patients with DED caused by Sjögren’s from other DED…

Introducing immunosuppressive or biological therapies early in people with Sjögren’s syndrome may prevent its progression to a bodywide systemic condition, a study in France suggests. “In our study, we can see that the introduction of [immunosuppressive agents] or biotherapy in systemic forms is only effective in around 50% of…

Patients with primary Sjögren’s syndrome who have extra-glandular symptoms have higher levels of the chemokine CXCL9 than those only affected in the saliva and tear-producing glands, a study finds. CXCL9 is a small signaling molecule involved in the migration and maturation of lymphocytes, a type of immune cell thought…

People with primary Sjögren’s syndrome who’d never received treatment for it show disturbances in their gut microbiota similar to what’s seen in systemic lupus erythematosus (SLE), another chronic autoimmune disorder, a study in China reports. Gut microbiota are microorganisms in the gastrointestinal tract — bacteria, fungi, and viruses —…