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January 16, 2020January 21, 2020

Potential Sjogren’s Therapy LOU064 Shows Promise in Early Lab Studies, Healthy Volunteers

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LOU064, an inhibitor of the Bruton tyrosine kinase (BTK) protein, is able to reduce the activation of B-cells both in lab dishes and in animal models, suggesting it has ... Read more

January 9, 2020January 15, 2020

Alpine’s Dual Inhibitor ALPN-101 Reduces Immune Cell Activation in Preclinical Models of Sjögren’s Syndrome

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Alpine Immune Sciences‘ ALPN-101, a treatment for inflammatory and autoimmune diseases that works by inhibiting two key pathways — ICOS and CD38 — is better at reducing immune cell ... Read more

January 2, 2020January 9, 2020

Sjögren’s Patients Fall into 4 Distinct Groups Depending on Symptoms, Study Suggests

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Sjögren’s syndrome can be classified into four distinct groups based on symptoms, and these groupings may be suggestive of differences in underlying biology and even response to treatment, a ... Read more

December 18, 2019December 20, 2019

FDA Clears Satisfaite, Lubricant System for Vaginal Dryness, Common Sjögren’s Symptom

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FemmePharma has been given a 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market Satisfaite, a delivery system for intravaginal lubricants that relieve the vaginal dryness associated with ... Read more

December 12, 2019January 15, 2020

Pri-Med and SSF Team Up for Medical Education Session on Sjogren’s Syndrome

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Pri-Med and the Sjogren’s Syndrome Foundation (SSF) recently partnered to present a continuing medical education session in Boston on the systemic autoimmune disease. Held Dec. 4 on the opening ... Read more

December 6, 2019December 6, 2019

HHS Secretary Alex Azar Touts White House Efforts to Cure Rare Diseases

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Despite skyrocketing healthcare costs, President Trump is committed to protecting the 30 million or so Americans with rare diseases and ensuring timely, affordable access to lifesaving treatments, the nation’s ... Read more

December 5, 2019December 20, 2019

Orencia Fails to Reduce Disease Activity in Patients with Early Active Primary Sjögren’s Syndrome, Trial Shows

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Orencia (abatacept), an immunotherapy used in rheumatic diseases, failed to reduce disease activity in patients with early active primary Sjögren’s syndrome after 24 weeks of treatment, results from the ... Read more

November 14, 2019

Rare Disease Film Festival Highlights Patient and Researcher Unity

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Rare disease-themed videos glowed on a large screen before an audience of people in wheelchairs, with crutches, and bearing oxygen tanks this Nov. 9 and 10 in San Francisco. ... Read more

November 14, 2019

Non-invasive Test May Help Diagnose Peripheral Nerve Damage in Sjögren’s Patients, Study Suggests

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A non-invasive test that measures nerve conduction through surface electrodes may help diagnose polyneuropathy — damage to multiple nerves outside the brain and spinal cord — in patients with ... Read more

November 7, 2019December 12, 2019

Recurrent Aseptic Meningitis Can Be First Symptom of Sjögren’s Syndrome, Case Report Suggests

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Doctors should suspect primary Sjögren’s syndrome when examining patients, especially young women, with recurrent aseptic meningitis — a form of inflammation of the meninges, a membrane protecting the brain and spinal ... Read more

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